Effect of Inducers, Incubation Time and Heme Concentration on IC50 Value Variation in Anti-heme Crystallization Assay
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چکیده
منابع مشابه
Effect of Inducers, Incubation Time and Heme Concentration on IC50 Value Variation in Anti-heme Crystallization Assay
Heme detoxification through crystallization into hemozoin has been suggested as a good target for the development of screening assays for new antimalarials. However, comparisons among the data obtained from different experiments are difficult, and the IC(50) values (the concentrations of drug that are required to inhibit 50% of hemozoin formation) for the same drug vary widely. We studied the e...
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ژورنال
عنوان ژورنال: Tropical Medicine and Health
سال: 2011
ISSN: 1349-4147,1348-8945
DOI: 10.2149/tmh.2011-29